TIM 1 (HAVCR1) Human Recombinant Protein

CAT#: TP724699

Recombinant Human Tim-1 (C-mFc)

Specifications

Product Data

• Species: Human
• Protein Source: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Ser21-Gly295
• Tag: C-Mouse Fc
• Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Note: Recombinant Human Tim-1 (C-mFc) is produced by Human Cells. The target gene encoding Ser21-Gly295 is expressed with a C-mFc tag.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 26762
• UniProt ID: Q96D42
• Summary: Hepatitis A virus cellular receptor 1 is also known as HAVCR1, HAVCR, KIM1, TIM, TIM1, TIMD1, is widely expressed with highest levels in kidney and testis. The protein encoded by HAVCR1 gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. HAVCR1 may play a role in T-helper cell development, the regulation of asthma and allergic diseases and in kidney injury and repair. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus.