TREM1 Cynomolgus Recombinant Protein

CAT#: TP724697

Recombinant Cynomolgus TREM1 (C-His)

Specifications

Product Data

• Species: Cynomolgus
• Protein Source: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Thr21-Pro201
• Tag: C-His
• Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Note: Recombinant Cynomolgus TREM1 (C-His) is produced by Human Cells. The target gene encoding Thr21-Pro201 is expressed with a C-His tag.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 693558
• Summary: Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) is a transmembrane protein with a single Ig-like domain. TREM-1 associates with the adapter protein, DAP12, to deliver an activating signal. TREM-1 is expressed on blood neutrophils and monocytes, and the expression is up-regulated by bacterial LPS. TREM-1 is expressed at high levels on neutrophils of patients with microbial sepsis and in mice with a TREM-1/Fc fusion protein protected mice against LPS-induced shock. Human TREM-1 shares 42% sequence homology with mouse TREM-1.