Il17f Mouse Recombinant Protein

CAT#: TP724652

Recombinant Mouse Interleukin-17F/IL-17F (C-His)

Specifications

Product Data

• Species: Mouse
• Protein Source: Human 293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  R29-A161
• Tag: C-8His
• Buffer: Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4
• Note: Recombinant Mouse Interleukin-17F is produced by Human 293 Cells. The target gene encoding R29-A161 is expressed with a 8His tag at the C terminus.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 257630
• UniProt ID: Q7TNI7
• Summary: Interleukin-17F (IL-17F) is a secreted disulfide-linked homodimer that belongs to the IL-17 family. IL-17F is expressed in activated CD4+ T-cells and activated monocytes. IL-17 is commonly associated with allergic responses. It mediates the induction of neutrophilia in the lungs and the exacerbation of antigen-induced pulmonary allergic inflammation. IL-17 stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. It is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1.