PI3 (NM_002638) Human Recombinant Protein

CAT#: TP720751XL

Purified recombinant protein of Human peptidase inhibitor 3, skin-derived (PI3)

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Ala23-Gln117
• Tag: C-His
• Predicted MW: 11 kDa
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Storage: Store at -80°C.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_002629
• Locus ID: 5266
• UniProt ID: P19957
• Cytogenetics: 20q13.12
• Refseq Size: 579
• Refseq ORF: 351
• Synonyms: cementoin; ESI; SKALP; WAP3; WFDC14
• Summary: This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2014]
• Protein Families: Secreted Protein, Transmembrane