CCL3 (NM_002983) Human Recombinant Protein
CAT#: TP720049
Recombinant protein of human chemokine (C-C motif) ligand 3 (CCL3)
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Ser24-Ala92
|
Tag | Tag Free |
Predicted MW | 7.7 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl |
Bioactivity | ED50 is 3-10 ng/mL as determined by the ability of Recombinant CCL3 to chemoattract human CCR5 transfected BaF3 mouse proB cells. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_002974 |
Locus ID | 6348 |
UniProt ID | P10147, A0N0R1 |
Cytogenetics | 17q12 |
Synonyms | G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3 |
Summary | This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010] |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC418970 | CCL3 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY418970 | Transient overexpression lysate of chemokine (C-C motif) ligand 3 (CCL3) |
USD 436.00 |
|
PH310026 | CCL3 MS Standard C13 and N15-labeled recombinant protein (NP_002974) |
USD 3,255.00 |
|
TP310026 | Recombinant protein of human chemokine (C-C motif) ligand 3 (CCL3), 20 µg |
USD 867.00 |
|
TP790113 | Purified recombinant protein of Human chemokine (C-C motif) ligand 3 (CCL3), esidues 24-92aa, with N-terminal His tag, secretory expressed in HEK293 cells, 50ug |
USD 871.00 |
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