CCL3 (NM_002983) Human Recombinant Protein

CAT#: TP720049

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Recombinant protein of human chemokine (C-C motif) ligand 3 (CCL3)


 Product Datasheet for 'TP720049'

  View other "CCL3" proteins (9)

USD 300.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description Recombinant protein of human chemokine (C-C motif) ligand 3 (CCL3)
Species Human
Expression Host E. coli
Tag Tag Free
Predicted MW 7.7 kDa
Concentration Resuspend the protein to the desired concentration in proper buffer.
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.4.
Bioactivity ED50 is 3-10 ng/mL as determined by the ability of Recombinant CCL3 to chemoattract human CCR5 transfected BaF3 mouse proB cells.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq NP_002974
Locus ID 6348
Refseq Size 813
Cytogenetics 17q12
Refseq ORF 276
Synonyms G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3
Summary This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1. [provided by RefSeq, Sep 2010]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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