Myelin oligodendrocyte glycoprotein (MOG) (NM_001008228) Human Recombinant Protein
CAT#: TP720042XL
Recombinant protein of human myelin oligodendrocyte glycoprotein (MOG), transcript variant alpha3
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Gly30-Gly154
|
Tag | C-His |
Predicted MW | 15.2 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl |
Bioactivity | Tested for capability to induce EAE in rodents and monkeys |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_001008229 |
Locus ID | 4340 |
UniProt ID | Q16653, Q16653-3 |
Cytogenetics | 6p22.1 |
Synonyms | BTN6; BTNL11; MOGIG2; NRCLP7 |
Summary | The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
Protein Families | Transmembrane |
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