Bone Sialoprotein (IBSP) (NM_004967) Human Recombinant Protein
Purified recombinant protein of human integrin-binding sialoprotein (IBSP), with C-terminal DDK/His tag, expressed in human cells;
Product Datasheet for 'TP700288'
Specifications
Product Data | |
Description | Purified recombinant protein of human integrin-binding sialoprotein (IBSP), with C-terminal DDK/His tag, expressed in human cells; |
Species | Human |
Expression Host | HEK293 |
Tag | C-DDK/10xHis |
Predicted MW | 36 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | PBS, pH7.4, 10% glycerol |
Reference Data | |
RefSeq | NP_004958 |
Locus ID | 3381 |
Refseq Size | 1108 |
Cytogenetics | 4q22.1 |
Refseq ORF | 951 |
Synonyms | BNSP; BSP; BSP-II; SP-II |
Summary | The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | ECM-receptor interaction, Focal adhesion |
Documents
FAQs |
SDS |
Resources
Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC417619 | IBSP HEK293T cell transient overexpression lysate (as WB positive control) |
USD 95.00 |
|
TP700289 | Purified recombinant protein of human integrin-binding sialoprotein (IBSP), with C-terminal DDK/His tag, expressed in human cells; |
USD 748.00 |
|
LY417619 | Transient overexpression lysate of integrin-binding sialoprotein (IBSP) |
USD 315.00 |
USD 335.00