DNA Ligase I(LIG1) (NM_000234) Human Recombinant Protein

CAT#: TP310760

Recombinant protein of human ligase I, DNA, ATP-dependent (LIG1)

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 Product Datasheet for 'TP310760'

USD 438.00

USD 730.00


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In Stock

Size
    • 20 ug

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Specifications

Product Data
Description Recombinant protein of human ligase I, DNA, ATP-dependent (LIG1)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC210760. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-MYC/DDK
Predicted MW 101.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Reference Data
RefSeq NP_000225
Locus ID 3978
Refseq Size 3083
Cytogenetics 19q13.33
Refseq ORF 2757
Synonyms MGC117397; MGC130025
Summary This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].
Protein Families
Protein Pathways
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