Glucose 6 Phosphate Dehydrogenase (G6PD) (NM_001042351) Human Recombinant Protein

CAT#: TP301807

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Recombinant protein of human glucose-6-phosphate dehydrogenase (G6PD), transcript variant 2


 Product Datasheet for 'TP301807'

  View other "G6PD" proteins (9)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human glucose-6-phosphate dehydrogenase (G6PD), transcript variant 2
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 59.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001035810
Locus ID 2539
Refseq Size 2295
Cytogenetics Xq28
Refseq ORF 1545
Synonyms G6PD1
Summary This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Glutathione metabolism, Metabolic pathways, Pentose phosphate pathway

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