Glucose 6 Phosphate Dehydrogenase(G6PD) (NM_000402) Human Recombinant Protein

CAT#: TP320625

Recombinant protein of human glucose-6-phosphate dehydrogenase (G6PD), transcript variant 1


 Product Datasheet for 'TP320625'

 Cited in 1 publication.

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human glucose-6-phosphate dehydrogenase (G6PD), transcript variant 1
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC220625. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-MYC/DDK
Predicted MW 62.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at –80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Bioactivity Acetylation substrate (PMID: 27356773)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_000393
Locus ID 2539
Refseq Size 2395
Cytogenetics Xq28
Refseq ORF 1635
Synonyms G6PD1; G6PD1
Summary This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Pentose phosphate pathway, Glutathione metabolism, Metabolic pathways

Citations (1)

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