MIP4 / CCL18 (22-89, His-tag) Human Protein

CAT#: AR09793PU-S

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MIP4 / CCL18 (22-89, His-tag) human recombinant protein, 10 µg



USD 330.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description MIP4 / CCL18 (22-89, His-tag) human recombinant protein, 10 µg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MGSSHHHHHH SSGLVPRGSH MGSHMQVGTN KELCCLVYTS WQIPQKFIVD YSETSPQCPK PGVILLTKRG RQICADPNKK WVQKYISDLK LNA
Tag His-tag
Predicted MW 10.4 kDa
Concentration 0.25 mg/ml (determined by Bradford assay)
Purity >95%
Buffer Presentation State: Purified
State: Liquid purified peptide
Buffer System: 10mM Sodium Citrate pH 3.5, 10% Glycerol
Endotoxin < 1.0 EU per 1 μg of protein (determined by LAL method )
Preparation Liquid purified peptide
Protein Description Recombinant human CCL18, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_002979
Locus ID 6362
Cytogenetics 17q12
Synonyms AMAC-1; AMAC1; CKb7; DC-CK1; DCCK1; MIP-4; PARC; SCYA18
Summary This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq, Sep 2014]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction

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