beta Casein (CSN2) (NM_001891) Human Mass Spec Standard

CAT#: PH323777

CSN2 MS Standard C13 and N15-labeled recombinant protein (NP_001882)

Product Images

Coomassie blue staining of purified CSN2 protein (Cat# TP323777). The protein was produced from HEK293T cells transfected with CSN2 cDNA clone (Cat# RC223777) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC223777
• Predicted MW: 25.4 kDa
• Protein Sequence:
  Sequence Link

  >RC223777 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MKVLILACLVALALARETIESLSSSEESITEYKQKVEKVKHEDQQQGEDEHQDKIYPSFQPQPLIYPFVE
  PIPYGFLPQNILPLAQPAVVLPVPQPEIMEVPKAKDTVYTKGRVMPVLKSPTIPFFDPQIPKLTDLENLH
  LPLPLLQPLMQQVPQPIPQTLALPPQPLWSVPQPKVLPIPQQVVPYPQRAVPVQALLLNQELLLNPTHQI
  YPVTQPLAPVHNPISV
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3
• Storage: Store at -80°C. Avoid repeated freeze-thaw cycles.
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_001882
• RefSeq Size: 1078
• RefSeq ORF: 678
• Synonyms: CASB; PDC213
• Locus ID: 1447
• UniProt ID: P05814, W5RWE1
• Cytogenetics: 4q13.3
• Summary: This gene is a member of the beta casein family. There are two types of casein protein, beta (encoded by this gene) and kappa, both of which are secreted in human milk. Beta casein is the principal protein in human milk and the primary source of essential amino acids for a suckling infant. Beta and kappa casein proteins acting together form spherical micelles which bind within them important dietary minerals, such as calcium and phosphorous. In addition, the C-terminal 14 aa of the protein has antimicrobial activity, especially in preterm milk, displaying antibacterial activity against S. aureus and Y. enterocolitica. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2020]
• Protein Families: Secreted Protein