PANK1 (NM_138316) Human Mass Spec Standard

CAT#: PH321519

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PANK1 MS Standard C13 and N15-labeled recombinant protein (NP_612189)

Product Datasheet for 'PH321519'

  View other "PANK1" proteins (9)

USD 2,055.00

3 Weeks

    • 10 ug

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Product Data
Description PANK1 MS Standard C13 and N15-labeled recombinant protein (NP_612189)
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221519
Predicted MW 35.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_612189
RefSeq Size 2525
RefSeq ORF 942
Synonyms PANK
Locus ID 53354
Cytogenetics 10q23.31
Summary This gene encodes a member of the pantothenate kinase family. Pantothenate kinases are key regulatory enzymes in the biosynthesis of coenzyme A (CoA). The encoded protein catalyzes the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene and an intronic miRNA on the same strand are co-regulated by the tumor suppressor p53 (see PMID 20833636). [provided by RefSeq, Apr 2011]
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Pantothenate and CoA biosynthesis


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