GABA A Receptor alpha 5 (GABRA5) (NM_000810) Human Mass Spec Standard
CAT#: PH316541
GABRA5 MS Standard C13 and N15-labeled recombinant protein (NP_000801)
Specifications
Product Data | |
Tag | C-Myc/DDK |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC216541 |
Predicted MW | 52.1 kDa |
Protein Sequence |
>Peptide sequence encoded by RC216541
Blue=ORF Red=Cloning site Green=Tag(s) MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGLG ERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNG KKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTN GSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQ VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT KRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSE SKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV Recombinant protein using RC216541 also available, TP316541M |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_000801 |
RefSeq Size | 2352 |
RefSeq ORF | 1386 |
Synonyms | DEE79; EIEE79 |
Locus ID | 2558 |
UniProt ID | P31644 |
Cytogenetics | 15q12 |
Summary | GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane |
Protein Pathways | Neuroactive ligand-receptor interaction |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400284 | GABRA5 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 206.00 |
|
LC431938 | GABRA5 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY400284 | Transient overexpression lysate of gamma-aminobutyric acid (GABA) A receptor, alpha 5 (GABRA5), transcript variant 1 |
USD 665.00 |
|
LY431938 | Transient overexpression lysate of gamma-aminobutyric acid (GABA) A receptor, alpha 5 (GABRA5), transcript variant 2 |
USD 436.00 |
|
TP316541 | Recombinant protein of human gamma-aminobutyric acid (GABA) A receptor, alpha 5 (GABRA5), 20 µg |
USD 867.00 |
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