GGPS1 (NM_004837) Human Mass Spec Standard

CAT#: PH302699

GGPS1 MS Standard C13 and N15-labeled recombinant protein (NP_004828)

Product Images

Coomassie blue staining of purified GGPS1 protein (Cat# TP302699). The protein was produced from HEK293T cells transfected with GGPS1 cDNA clone (Cat# RC202699) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC202699
• Predicted MW: 34.9 kDa
• Protein Sequence:
  Sequence Link

  >RC202699 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MEKTQETVQRILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNS
  KLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGLDIYWRDNYTCPT
  EEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTE
  GKFSFPTIHAIWSRPESTQVQNILRQRTENIDIKKYCVHYLEDVGSFEYTRNTLKELEAKAYKQIDARGG
  NPELVALVKHLSKMFKEENE
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3
• Storage: Store at -80°C. Avoid repeated freeze-thaw cycles.
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_004828
• RefSeq Size: 2921
• RefSeq ORF: 900
• Synonyms: GGPPS; GGPPS1
• Locus ID: 9453
• UniProt ID: O95749
• Cytogenetics: 1q42.3
• Summary: This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq, Sep 2010]
• Protein Pathways: Metabolic pathways, Terpenoid backbone biosynthesis