Noxa (PMAIP1) (NM_021127) Human Mass Spec Standard

CAT#: PH302071

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PMAIP1 MS Standard C13 and N15-labeled recombinant protein (NP_066950)

USD 3,255.00

3 Weeks*

    • 10 ug

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Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202071
Predicted MW 5.8 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_066950
RefSeq Size 1885
RefSeq ORF 162
Synonyms APR; NOXA
Locus ID 5366
UniProt ID Q13794, A0A0S2Z490
Cytogenetics 18q21.32
Summary This gene belongs to a pro-apoptotic subfamily within the BCL-2 protein family, referred to as the BCL-2 homology domain 3 (BH3)-only subfamily, which determine whether a cell commits to apoptosis. In response to death-inducing stimuli, BH3-only members inhibit the anti-apoptotic BCL-2 family members, which under steady-state conditions keep the multi-BH domain proteins BAX and BAK, in an inactive state. [provided by RefSeq, Aug 2020]
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways p53 signaling pathway


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