Adenosine A2b Receptor (ADORA2B) Human Gene Knockout Kit (CRISPR)

CAT#: KN206623RB

ADORA2B - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: Adenosine A2b Receptor
• Locus ID: 136
• Components:

  KN206623G1, Adenosine A2b Receptor gRNA vector 1 in pCas-Guide CRISPR vector

  KN206623G2, Adenosine A2b Receptor gRNA vector 2 in pCas-Guide CRISPR vector

  KN206623RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_000676
• UniProt ID: P29275
• Synonyms: ADORA2
• Summary: This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]