Mouse Kif26b activation kit by CRISPRa

CAT#: GA215987

Kif26b CRISPRa kit - CRISPR gene activation of mouse kinesin family member 26B

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Kif26b
• Locus ID: 269152
• Kit Components:

  GA215987G1, Kif26b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA215987G2, Kif26b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA215987G3, Kif26b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001161665, NM_177757
• UniProt ID: Q7TNC6
• Synonyms: 4832420M10; BC056349; D230039L06Rik
• Summary: Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Although it seems to lack ATPase activity it is constitutively associated with microtubules.[UniProtKB/Swiss-Prot Function]