Mouse Aaas activation kit by CRISPRa

CAT#: GA213654

Aaas CRISPRa kit - CRISPR gene activation of mouse achalasia, adrenocortical insufficiency, alacrimia

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Aaas
• Locus ID: 223921
• Kit Components:

  GA213654G1, Aaas gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA213654G2, Aaas gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA213654G3, Aaas gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_153416
• UniProt ID: P58742
• Synonyms: AAA; ADRACALA; D030041N15Rik; GL003
• Summary: Plays a role in the normal development of the peripheral and central nervous system. Required for the correct localization of aurora kinase AURKA and the microtubule minus end-binding protein NUMA1 as well as a subset of AURKA targets which ensures proper spindle formation and timely chromosome alignment.[UniProtKB/Swiss-Prot Function]