Mouse Chrna3 activation kit by CRISPRa

CAT#: GA212356

Chrna3 CRISPRa kit - CRISPR gene activation of mouse cholinergic receptor, nicotinic, alpha polypeptide 3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Chrna3
• Locus ID: 110834
• Kit Components:

  GA212356G1, Chrna3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA212356G2, Chrna3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA212356G3, Chrna3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_145129
• UniProt ID: Q8R4G9
• Synonyms: (a)3; A730007P14Rik; Acra-3; Acra3
• Summary: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.[UniProtKB/Swiss-Prot Function]