Mouse Cdca2 activation kit by CRISPRa

CAT#: GA212163

Cdca2 CRISPRa kit - CRISPR gene activation of mouse cell division cycle associated 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Cdca2
• Locus ID: 108912
• Kit Components:

  GA212163G1, Cdca2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA212163G2, Cdca2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA212163G3, Cdca2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001110162, NM_175384
• UniProt ID: Q14B71
• Synonyms: 2610311M19Rik; AI586158
• Summary: Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates (By similarity).[UniProtKB/Swiss-Prot Function]