Mouse Kdelr2 activation kit by CRISPRa

CAT#: GA207022

Kdelr2 CRISPRa kit - CRISPR gene activation of mouse KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Kdelr2
• Locus ID: 66913
• Kit Components:

  GA207022G1, Kdelr2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA207022G2, Kdelr2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA207022G3, Kdelr2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_025841
• UniProt ID: Q9CQM2
• Synonyms: 1110007A14Rik
• Summary: Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum (By similarity). Binding is pH dependent, and is optimal at pH 5-5.4 (By similarity).[UniProtKB/Swiss-Prot Function]