Mouse Vegfc activation kit by CRISPRa

CAT#: GA204593

Vegfc CRISPRa kit - CRISPR gene activation of mouse vascular endothelial growth factor C

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Vegfc
• Locus ID: 22341
• Kit Components:

  GA204593G1, Vegfc gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA204593G2, Vegfc gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA204593G3, Vegfc gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009506
• UniProt ID: P97953
• Synonyms: AW228853; VEGF-C
• Summary: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates KDR/VEGFR2 and FLT4/VEGFR3 receptors.[UniProtKB/Swiss-Prot Function]