Mouse Ptgs1 activation kit by CRISPRa

CAT#: GA203459

Ptgs1 CRISPRa kit - CRISPR gene activation of mouse prostaglandin-endoperoxide synthase 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Ptgs1
• Locus ID: 19224
• Kit Components:

  GA203459G1, Ptgs1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA203459G2, Ptgs1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA203459G3, Ptgs1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_008969
• UniProt ID: P22437
• Synonyms: Cox-1; Cox-3; COX1; PGHS-1; Pghs1; PHS 1
• Summary: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. [provided by RefSeq, Jan 2014]