Mouse Mcl1 activation kit by CRISPRa

CAT#: GA202602

Mcl1 CRISPRa kit - CRISPR gene activation of mouse myeloid cell leukemia sequence 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Mcl1
• Locus ID: 17210
• Kit Components:

  GA202602G1, Mcl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202602G2, Mcl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202602G3, Mcl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_008562
• UniProt ID: P97287
• Synonyms: AW556805; Mcl-1
• Summary: Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 2 has antiapoptotic activity.[UniProtKB/Swiss-Prot Function]