Mouse Adcyap1 activation kit by CRISPRa

CAT#: GA200078

Adcyap1 CRISPRa kit - CRISPR gene activation of mouse adenylate cyclase activating polypeptide 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Adcyap1
• Locus ID: 11516
• Kit Components:

  GA200078G1, Adcyap1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA200078G2, Adcyap1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA200078G3, Adcyap1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009625
• UniProt ID: O70176
• Synonyms: PACAP
• Summary: This gene encodes a member of the glucagon superfamily of hormones that have important roles in growth and metabolism. The encoded protein undergoes proteolytic processing to generate mature peptides that function as hypophysiotropic hormones, neurotransmitters, neuromodulators and vasoregulators. Mice lacking the encoded protein exhibit a high rate of early mortality. The surviving adult animals lacking the encoded protein exhibit decreased anxiety, hyperactive behavior and impaired steroidogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015]