Human GLRA4 activation kit by CRISPRa

CAT#: GA118514

GLRA4 CRISPRa kit - CRISPR gene activation of human glycine receptor alpha 4

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: GLRA4
• Locus ID: 441509
• Kit Components:

  GA118514G1, GLRA4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA118514G2, GLRA4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA118514G3, GLRA4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001024452, NM_001172285
• Synonyms: glycine receptor, alpha 4; glycine receptor, alpha 4 subunit; OTTHUMP00000023760
• Summary: This gene encodes a glycine receptor and member of the ligand-gated ion channel family of proteins. The encoded protein is missing the fourth transmembrane region compared to related proteins in mouse and rat, and experimental data suggests that the human protein is functionally inactive. However, there is strong evidence to support transcription of this gene. As a result, RefSeq, in collaboration with Ensembl-GENCODE, has determined that this locus is best described as a transcribed pseudogene. [provided by RefSeq, Aug 2019]