Human KRT25 activation kit by CRISPRa

CAT#: GA115601

KRT25 CRISPRa kit - CRISPR gene activation of human keratin 25

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: KRT25
• Locus ID: 147183
• Kit Components:

  GA115601G1, KRT25 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115601G2, KRT25 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115601G3, KRT25 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_181534
• UniProt ID: Q7Z3Z0
• Synonyms: ARWH3; KRT24IRS1; KRT25A
• Summary: This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]