Human C19orf12 activation kit by CRISPRa

CAT#: GA113216

C19orf12 CRISPRa kit - CRISPR gene activation of human chromosome 19 open reading frame 12

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: C19orf12
• Locus ID: 83636
• Kit Components:

  GA113216G1, C19orf12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA113216G2, C19orf12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA113216G3, C19orf12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001031726, NM_001256046, NM_001256047, NM_001282929, NM_001282930, NM_001282931, NM_031448, NR_045690, NR_045691, NR_045692
• UniProt ID: Q9NSK7
• Synonyms: NBIA3; NBIA4; SPG43
• Summary: This gene encodes a small transmembrane protein. Mutations in this gene are a cause of neurodegeneration with brain iron accumulation-4 (NBIA4), but the specific function of the encoded protein is unknown. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]