Human TSPAN14 activation kit by CRISPRa

CAT#: GA113095

TSPAN14 CRISPRa kit - CRISPR gene activation of human tetraspanin 14

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TSPAN14
• Locus ID: 81619
• Kit Components:

  GA113095G1, TSPAN14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA113095G2, TSPAN14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA113095G3, TSPAN14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001128309, NM_030927, NM_001351266, NM_001351267, NM_001351268, NM_001351269, NM_001351270, NM_001351271, NM_001351272
• UniProt ID: Q8NG11
• Synonyms: DC-TM4F2; TM4SF14
• Summary: Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26668317, PubMed:23035126, PubMed:26686862). Negatively regulates ADAM10-mediated cleavage of GP6 (By similarity). Promotes ADAM10-mediated cleavage of CDH5 (By similarity).[UniProtKB/Swiss-Prot Function]