Human OCIAD1 activation kit by CRISPRa

CAT#: GA110389

OCIAD1 CRISPRa kit - CRISPR gene activation of human OCIA domain containing 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: OCIAD1
• Locus ID: 54940
• Kit Components:

  GA110389G1, OCIAD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110389G2, OCIAD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110389G3, OCIAD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001079839, NM_001079840, NM_001079841, NM_001079842, NM_001168254, NM_017830
• UniProt ID: Q9NX40
• Synonyms: ASRIJ; OCIA; TPA018
• Summary: Maintains stem cell potency (By similarity). Increases STAT3 phosphorylation and controls ERK phosphorylation (By similarity). May act as a scaffold, increasing STAT3 recruitment onto endosomes (By similarity). Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer (PubMed:20515946).[UniProtKB/Swiss-Prot Function]