Human RAB3GAP1 activation kit by CRISPRa

CAT#: GA107921

RAB3GAP1 CRISPRa kit - CRISPR gene activation of human RAB3 GTPase activating protein catalytic subunit 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: RAB3GAP1
• Locus ID: 22930
• Kit Components:

  GA107921G1, RAB3GAP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107921G2, RAB3GAP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107921G3, RAB3GAP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001172435, NM_012233
• UniProt ID: Q15042
• Synonyms: P130; RAB3GAP; RAB3GAP130; WARBM1
• Summary: This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]