Human GADD45G activation kit by CRISPRa

CAT#: GA107481

GADD45G CRISPRa kit - CRISPR gene activation of human growth arrest and DNA damage inducible gamma

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: GADD45G
• Locus ID: 10912
• Kit Components:

  GA107481G1, GADD45G gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107481G2, GADD45G gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107481G3, GADD45G gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006705
• UniProt ID: O95257
• Synonyms: CR6; DDIT2; GADD45gamma; GRP17
• Summary: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008]