Human NPC2 activation kit by CRISPRa

CAT#: GA107236

NPC2 CRISPRa kit - CRISPR gene activation of human NPC intracellular cholesterol transporter 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: NPC2
• Locus ID: 10577
• Kit Components:

  GA107236G1, NPC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107236G2, NPC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107236G3, NPC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006432, NM_001363688
• UniProt ID: P61916
• Synonyms: EDDM1; HE1
• Summary: This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq, Jul 2008]