Human SNX3 activation kit by CRISPRa

CAT#: GA105790

SNX3 CRISPRa kit - CRISPR gene activation of human sorting nexin 3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SNX3
• Locus ID: 8724
• Kit Components:

  GA105790G1, SNX3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105790G2, SNX3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105790G3, SNX3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001300928, NM_001300929, NM_003795, NM_152827, NM_152828
• UniProt ID: O60493
• Synonyms: Grd19; MCOPS8; SDP3
• Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking. A pseudogene of this gene is present on the sex chromosomes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]