Human CXCL5 activation kit by CRISPRa

CAT#: GA104335

CXCL5 CRISPRa kit - CRISPR gene activation of human C-X-C motif chemokine ligand 5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CXCL5
• Locus ID: 6374
• Kit Components:

  GA104335G1, CXCL5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104335G2, CXCL5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104335G3, CXCL5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002994
• UniProt ID: P42830
• Synonyms: ENA-78; SCYB5
• Summary: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013]