Human EPB41 activation kit by CRISPRa

CAT#: GA101414

EPB41 CRISPRa kit - CRISPR gene activation of human erythrocyte membrane protein band 4.1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: EPB41
• Locus ID: 2035
• Kit Components:

  GA101414G1, EPB41 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101414G2, EPB41 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101414G3, EPB41 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001166005, NM_001166006, NM_001166007, NM_004437, NM_203342, NM_203343
• UniProt ID: P11171
• Synonyms: 4.1R; EL1; HE
• Summary: The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Oct 2009]