Irf2bpl (NM_001012470) Rat Tagged ORF Clone Lentiviral Particle

CAT#: RR211529L4V

Lenti ORF particles, Irf2bpl (GFP-tagged ORF) - Rat polyglutamine-containing protein (Pqcp), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: mGFP
• Symbol: Irf2bpl
• Synonyms: Eap1; Pqcp; RGD1310994
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001012470
• ORF Size: 2349 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RR211529).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001012470.1, NP_001012488.1
• RefSeq Size: 2352 bp
• RefSeq ORF: 2352 bp
• Locus ID: 314329
• UniProt ID: Q5EIC4
• Cytogenetics: 6q31
• Gene Summary: Probable E3 ubiquitin protein ligase involved in the proteasome-mediated ubiquitin-dependent degradation of target proteins. Through the degradation of CTNNB1, functions downstream of FOXF2 to negatively regulate the Wnt signaling pathway. Probably plays a role in the development of the central nervous system and in neuronal maintenance (By similarity). Also acts as a transcriptional regulator of genes controlling female reproductive function. May play a role in gene transcription by transactivating GNRH1 promoter and repressing PENK promoter.[UniProtKB/Swiss-Prot Function]