Plekhf1 (NM_001013148) Rat Tagged ORF Clone Lentiviral Particle

CAT#: RR211451L4V

Lenti ORF particles, Plekhf1 (GFP-tagged ORF) - Rat pleckstrin homology domain containing, family F (with FYVE domain) member 1 (Plekhf1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: mGFP
• Symbol: Plekhf1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001013148
• ORF Size: 837 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RR211451).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001013148.1, NP_001013166.1
• RefSeq Size: 1504 bp
• RefSeq ORF: 840 bp
• Locus ID: 308543
• UniProt ID: Q68FU1
• Cytogenetics: 1q21
• Gene Summary: May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8 (By similarity).[UniProtKB/Swiss-Prot Function]