Bace2 (NM_001002802) Rat Tagged ORF Clone Lentiviral Particle

CAT#: RR205199L4V

Lenti ORF particles, Bace2 (GFP-tagged ORF) - Rat beta-site APP-cleaving enzyme 2 (Bace2), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: mGFP
• Symbol: Bace2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001002802
• ORF Size: 1542 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RR205199).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001002802.1, NP_001002802.1
• RefSeq Size: 1545 bp
• RefSeq ORF: 1545 bp
• Locus ID: 288227
• UniProt ID: Q6IE75
• Cytogenetics: 11q12
• Gene Summary: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672 (By similarity). Responsible also for the proteolytic processing of CLTRN in pancreatic beta cells (By similarity).[UniProtKB/Swiss-Prot Function]