CD105 (ENG) (NM_001114753) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC226069L1V

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  • LentiORF®

Lenti ORF particles, ENG (Myc-DDK tagged) - Human endoglin (ENG), transcript variant 1, 200ul, >10^7 TU/mL



USD 1,468.00


Availability*
3 Weeks

Size
    • 200 ul


Product images

Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol ENG
Synonyms END; HHT1; ORW1
Mammalian Cell Selection None
Vector pLenti-C-Myc-DDK
ACCN NM_001114753
ORF Size 1974 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC226069).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001114753.1
RefSeq ORF 1977 bp
Locus ID 2022
UniProt ID P17813
Cytogenetics 9q34.11
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
MW 70.64 kDa
Gene Summary This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.