AASS (NM_005763) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC224831L3V

Lenti ORF particles, AASS (Myc-DDK tagged) - Human aminoadipate-semialdehyde synthase (AASS), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: AASS
• Synonyms: LKR/SDH; LKRSDH; LORSDH
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_005763
• ORF Size: 2778 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224831).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005763.2
• RefSeq Size: 3233 bp
• RefSeq ORF: 2781 bp
• Locus ID: 10157
• UniProt ID: Q9UDR5
• Cytogenetics: 7q31.32
• Domains: Saccharop_dh, AlaDh_PNT_C, AlaDh_PNT_N
• Protein Families: Druggable Genome
• Protein Pathways: Lysine biosynthesis, Lysine degradation, Metabolic pathways
• MW: 102 kDa
• Gene Summary: This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. [provided by RefSeq, Jul 2008]