SIAH3 (NM_198849) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC223820L1V

Lenti ORF particles, SIAH3 (Myc-DDK tagged) - Human seven in absentia homolog 3 (Drosophila) (SIAH3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: SIAH3
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_198849
• ORF Size: 807 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC223820).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_198849.2
• RefSeq Size: 4005 bp
• RefSeq ORF: 810 bp
• Locus ID: 283514
• UniProt ID: Q8IW03
• Cytogenetics: 13q14.13
• MW: 30.5 kDa
• Gene Summary: Negative regulator of PRKN translocation to damaged mitochondria. Acts probably by destabilizing PINK1 protein, hence inhibiting PRKN targeting to dysfunctional depolarized mitochondria.[UniProtKB/Swiss-Prot Function]