VNN1 (NM_004666) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC223462L2V

Lenti ORF particles, VNN1 (mGFP-tagged) - Human vanin 1 (VNN1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: VNN1
• Synonyms: HDLCQ8; Tiff66
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_004666
• ORF Size: 1539 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC223462).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004666.1, NP_004657.1
• RefSeq Size: 3109 bp
• RefSeq ORF: 1542 bp
• Locus ID: 8876
• UniProt ID: O95497
• Cytogenetics: 6q23.2
• Protein Pathways: Pantothenate and CoA biosynthesis
• MW: 57.02 kDa
• Gene Summary: This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. [provided by RefSeq, Feb 2009]