HIST1H2BC (H2BC4) (NM_003526) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC217796L2V

Lenti ORF particles, HIST1H2BC (mGFP-tagged) - Human histone cluster 1, H2bc (HIST1H2BC), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: H2BC4
• Synonyms: dJ221C16.3; H2B.1; H2B/l; H2BC6; H2BC7; H2BC8; H2BC10; H2BFL; HIST1H2BC
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_003526
• ORF Size: 378 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217796).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003526.2
• RefSeq Size: 438 bp
• RefSeq ORF: 381 bp
• Locus ID: 8347
• UniProt ID: P62807
• Cytogenetics: 6p22.2
• Domains: H2B, histone
• Protein Families: Stem cell - Pluripotency
• Protein Pathways: Systemic lupus erythematosus
• MW: 13.7 kDa
• Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The protein has antibacterial and antifungal antimicrobial activity. The main transcript variant of this gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. This transcript variant lacks a polyA tail but instead contains a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Apr 2020]