ZFX (NM_003410) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC214045L2V

Lenti ORF particles, ZFX (mGFP-tagged) - Human zinc finger protein, X-linked (ZFX), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: ZFX
• Synonyms: ZNF926
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_003410
• ORF Size: 2415 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214045).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003410.2
• RefSeq Size: 5811 bp
• RefSeq ORF: 2418 bp
• Locus ID: 7543
• UniProt ID: P17010
• Cytogenetics: Xp22.11
• Domains: Zfx_Zfy_act, zf-C2H2
• Protein Families: Transcription Factors
• MW: 90.3 kDa
• Gene Summary: This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2010]