SEC24B (NM_006323) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC211593L4V

Lenti ORF particles, SEC24B (mGFP-tagged)-Human SEC24 family, member B (S. cerevisiae) (SEC24B), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: SEC24B
• Synonyms: SEC24
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_006323
• ORF Size: 3804 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC211593).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006323.1, NP_006314.1
• RefSeq Size: 4758 bp
• RefSeq ORF: 3807 bp
• Locus ID: 10427
• UniProt ID: O95487
• Cytogenetics: 4q25
• Domains: zf-Sec23_Sec24, Sec23_trunk, Sec23_helical, Gelsolin
• MW: 137.2 kDa
• Gene Summary: The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein is thought to be a cargo-binding component of the COPII vesicle, and is thought to be involved in the transport of secretory proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in this gene have been associated with neural tube defects, and are thought to be a result of a disruption in interactions with the protein encoded by the VANGL planar cell polarity protein 2 (VANGL2) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]