TNFRSF4 (NM_003327) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC211253L3V

Lenti ORF particles, TNFRSF4 (Myc-DDK tagged) - Human tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: TNFRSF4
• Synonyms: ACT35; CD134; IMD16; OX40; TXGP1L
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_003327
• ORF Size: 831 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC211253).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003327.2
• RefSeq Size: 1120 bp
• RefSeq ORF: 834 bp
• Locus ID: 7293
• UniProt ID: P43489
• Cytogenetics: 1p36.33
• Domains: TNFR
• Protein Families: Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction
• MW: 29.3 kDa
• Gene Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]