IL23 (IL23A) (NM_016584) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209680L2V

Lenti ORF particles, IL23A (mGFP-tagged) - Human interleukin 23, alpha subunit p19 (IL23A), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: IL23
• Synonyms: IL-23; IL-23A; IL23P19; P19; SGRF
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_016584
• ORF Size: 567 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209680).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_016584.2
• RefSeq Size: 1049 bp
• RefSeq ORF: 570 bp
• Locus ID: 51561
• UniProt ID: Q9NPF7
• Cytogenetics: 12q13.3
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• MW: 20.8 kDa
• Gene Summary: This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq, Jul 2008]