SUOX (NM_000456) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209066L3V

Lenti ORF particles, SUOX (Myc-DDK tagged) - Human sulfite oxidase (SUOX), nuclear gene encoding mitochondrial protein, transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: SUOX
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_000456
• ORF Size: 1635 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209066).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000456.2, NP_000447.2
• RefSeq Size: 2564 bp
• RefSeq ORF: 1638 bp
• Locus ID: 6821
• UniProt ID: P51687
• Cytogenetics: 12q13.2
• Domains: oxidored_molyb, heme_1, Mo-co_dimer
• Protein Families: Druggable Genome
• Protein Pathways: Sulfur metabolism
• MW: 60.3 kDa
• Gene Summary: Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins. [provided by RefSeq, Jul 2008]